Welcome to the MCM Laboratory @Houston Archive

Our previous lab home located at the heart of the Texas Medical Center in Houston:

Behavioral setup

Memory-related tasks: T maze, novel object recognition, object place recognition, contextual/auditory fear conditioning, inhibitory avoidance, morris water maze, self-administration.

Social interaction tasks: three-chamber test, direct social, ultrasonic vocalization recording.

Other behaviors: grooming, elevated plus maze test, forced swim test, tail-suspension test, nesting behaviors, open field test, conditioned place preference.

Drosophila behaviors: classical olfactory conditioning.

Electrophysiology setups

Whole cell recording, field recording and multi-electrode array.

Cellular experiments

We perform a wide battery of techniques, including brain slice treatment, immunohistochemistry, immunostaining, cell culture, cell sorting and tissue culture

Molecular experiments

Techniques that we performed in the lab include cloning, DNA/RNA extraction, RNA sequencing, q-PCR, Western blotting, polysome profiling, and ribosome profiling etc.

Microbial Genetics

Anaerobic chambers, germ-free facilities are available at BCM (not pictured here).

Surgery, Stereotaxic injections, EEG Recordings, Optogenetics

System Neuroscience: EEG recordings, stereotaxic viral injection and optogenetic stimulation.

The Costa-Mattioli Lab / Altos Labs

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Website contents curated by MCM, Yuwei Liu and Christina Myhre